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Molecular Biomarkers and Network Analyses of Neuron-type Connectivity Reveal Cloaked Insights into Hippocampal Function

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dc.contributor.advisor Ascoli, Giorgio A.
dc.contributor.author Rees, Christopher Loren
dc.creator Rees, Christopher Loren
dc.date.accessioned 2017-01-29T01:16:39Z
dc.date.available 2017-01-29T01:16:39Z
dc.date.issued 2016
dc.identifier.uri https://hdl.handle.net/1920/10604
dc.description.abstract To launch Hippocampome.org, a framework for classifying neuron types in the rodent hippocampus, we assembled >14,000 pieces of experimental evidence supporting knowledge of approximately 3,700 properties for 122 neuron types. This resource, the first comprehensive machine-readable neuron inventory for a mammalian cortical region, provides an opportunity to analyze the hippocampus in novel ways and garner unique insights into its intricate structure and enigmatic function. Here, I describe my two-pronged attack on the sub-cellular and cellular fronts.
dc.format.extent 207 pages
dc.language.iso en
dc.rights Copyright 2016 Christopher Loren Rees
dc.subject Neurosciences en_US
dc.subject Bioinformatics en_US
dc.subject Connectomics en_US
dc.subject Graph theory en_US
dc.subject Hippocampus en_US
dc.subject Molecular markers en_US
dc.subject Neuroinformatics en_US
dc.subject Neuron types en_US
dc.title Molecular Biomarkers and Network Analyses of Neuron-type Connectivity Reveal Cloaked Insights into Hippocampal Function
dc.type Dissertation
thesis.degree.level Ph.D.
thesis.degree.discipline Bioinformatics and Computational Biology
thesis.degree.grantor George Mason University


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