Mason Archival Repository Service

Germs on a Plane: The Transmission and Risks of Airplane-Borne Diseases

Show simple item record

dc.contributor.advisor Koblentz, Gregory
dc.contributor.author Sevilla, Nereyda Lucia
dc.creator Sevilla, Nereyda Lucia
dc.date.accessioned 2018-10-22T01:20:31Z
dc.date.available 2018-10-22T01:20:31Z
dc.date.issued 2017
dc.identifier.uri https://hdl.handle.net/1920/11287
dc.description.abstract Purpose: This dissertation explores the role of air travel in the spread of diseases, specifically the threat of pneumonic plague as a natural outbreak or after a bioterrorist attack. Introduction/Background: Air travel provides new means for diseases to spread internationally at unprecedented rates. This was evident in the 2003 Severe Acute Respiratory Syndrome (SARS) pandemic that killed over 800 people across 37 countries, the 2009 Influenza H1N1 epidemic which affected over 200 million individuals, and the 2014 Ebola outbreak that killed over 11,000 people. An aircraft has a role in disease spread both as a vector and incubator. Public health interventions including travel restrictions, entry and exit procedures, quarantine and isolation, and risk communication, are some of the current methods used to contain disease outbreaks. An outbreak of pneumonic plague, which has a high mortality rate, is spread from person to person, and is endemic to the United States, may challenge the effectiveness of these public health responses. Methods: This dissertation uses a mixed methods approach to evaluate the impact of aviation on the spread of infectious diseases and the effectiveness of different public health strategies. A compartment method of mathematical modeling is used to compare and contrast the spread of SARS, H1N1, and Ebola. In addition, hypothetical natural pneumonic plague outbreaks are modeled starting with 1 or 10 initial cases as well as bioterrorist attacks with Y. pestis that may infect 1, 10, 50, 100, or 1000 individuals to determine the potential spread over a six-month period. Results: All the graphical and numerical results indicate that SARS and H1N1 have a much greater impact in terms of infections and deaths than Ebola or pneumonic plague regardless of the initial number of infections. Modeling shows that the spread of pneumonic plague is minimal and should not be a major air travel concern if an individual becomes infected. Due to the rapid progression of pneumonic plague and the high likelihood of death, spread of the disease is highly unlikely to progress from the initial victims. Conclusion: This is the first type of research to compare, contrast, and model different diseases to determine the best scientific disease mitigation measures for the common air traveler. The threat of pneumonic plague is not from the disease, but from the potential psychological impact. To contain the outbreak of pneumonic plague, aviation and public health authorities should establish preventative infectious disease measures at airports, streamline contact procedures for ticketed passengers, expand the definition of “close contact,” and conduct widespread educational programs. The measures will put in place a foundation for containing any infectious disease and ensure that a natural or intentional pneumonic plague outbreak cannot be sustained.
dc.format.extent 230 pages
dc.language.iso en
dc.rights Copyright 2017 Nereyda Lucia Sevilla
dc.subject Public health en_US
dc.subject Public policy en_US
dc.subject Air travel en_US
dc.subject Biodefense en_US
dc.subject Infectious diseases en_US
dc.subject Plague en_US
dc.subject Spatiotemporal Epidemiological Modeler en_US
dc.subject Travel health en_US
dc.title Germs on a Plane: The Transmission and Risks of Airplane-Borne Diseases
dc.type Dissertation
thesis.degree.level Ph.D.
thesis.degree.discipline Biodefense
thesis.degree.grantor George Mason University


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search MARS


Browse

My Account

Statistics