Abstract:
The basic concept of our web tool is to develop an integrative analysis of target
prediction together with miRNA and gene expression data obtained from microarray data
of Drosophila. The web tool can be broadly classified into two parts: Query Section and
Analysis Section. The Query Section allows users to retrieve and browse different target
prediction databases including PITA, Miranda and TargetScan. The Analysis Section
depends upon the statistical approach to predicting the miRNA-mRNA targets. The
statistical part can be broadly classified into three components: A) The parametric
(Pearson) correlation), B) Distance Correlation and C) Brownian Covariance. Statistical
calculation was done in R. The graphical representation of the interaction would be
obtained by ggplot, an R package.
