Schar School of Policy and Government
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The Schar School of Policy and Government prepares undergraduate and graduate students to be leaders and managers who solve problems and advance the public good in all sectors and levels of government—in the United States and throughout the world.
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Browsing Schar School of Policy and Government by Subject "Biotechnology"
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Item Biotechnology Risk Assessment: Landscape and Options(George Mason University, 2018-03) Kirkpatrick, Jesse; Koblentz, Gregory D.; Palmer, Megan J.; Denton, Sarah W; Tiu, BruceItem Biotechnology Risk Assessment: State of the Field(George Mason University, 2017-12) Koblentz, Gregory D.; Kirkpatrick, Jesse; Palmer, Megan J.; Denton, Sarah W.; Tiu, Bruce; Kelsey, KelseyItem CRISPR Genome Editing: A Technical & Policy Primer(2018) Perello, EdwardItem Editing Biosecurity: Needs and Strategies for Governing Genome Editing(George Mason University, 2018-12) Kirkpatrick, Jesse; Koblentz, Gregory D.; Palmer, Megan J.; Perello, Edward; Relman, David A.; Denton, Sarah WItem Editing Biosecurity: Needs and Strategies for Governing Genome Editing, Executive Summary(George Mason University, 2018-12) Kirkpatrick, Jesse; Koblentz, Gregory D.; Palmer, Megan J.; Perello, Edward; Relman, David A.; Denton, Sarah WItem The CRISPR Revolution: Potential Impacts on Global Health Security(2018) Watters, KyleBiotechnology and medicine are constantly battling threats to global health security. Many modern techniques exist for detecting and predicting where outbreaks might occur and between small molecule drugs, like antibiotics, biologics, and vaccines, much progress has been made in treating diseases globally. However, outbreaks still frequently occur, and many pathogens exist for which there are no treatment. In this review, we paint a picture of the challenges faced in maintaining global health security and how a new wave of gene editing technologies can overcome them. We discuss a number of technologies that are actively developing CRISPR as a treatment or diagnostic tool as well as how CRISPR tools can affect drug development indirectly and speculate on what the near future for these research directions holds. Last, some of the risks associated with gene editing technologies and the efforts scientists are undertaking to mitigate them are covered. Overall, CRISPR and gene editing technologies are likely to have a positive influence on our global health security outlook, both as a form of treatment and detection tool as well as a force for increasing the rate of biological and drug discovery.