Autism spectrum disorder (ASD) is one of the most common neurodevelopmental disorders. Worldwide, ASD tends to have a prevalence of one in 100 children, with an estimated prevalence of 1 in 44 children, according to CDC’s ...
Epitopes, the regions of antigens that are detected by the immune system, have garnered considerable scientific interest in recent years due to their potential for influencing the development of novel medical countermeasures, ...
Continued advances in high-throughput sequencing have created new opportunities to discern microbiome composition from a variety of samples and to develop applications in ecological recycling efforts and health and disease ...
Influenza A Virus (IAV) is remarkably adept at surviving in human populations. IAV thrives even among populations with wide spread access to vaccines and anti-viral drugs, and continues to be a major cause of morbidity and ...
DNA polymerase III is a prokaryotic protein, which is usually not found in eukaryotes, however protein sequence databases contain hundreds of entries for eukaryotic proteins labeled or annotated as DNA polymerase III subunit ...
Secondary structure assignment (SSA) is the classification of each residue in a protein structure as helix, strand, or coil and, in this work, a new method for SSA is developed. SS is vital for stabilizing the overall ...
Mutations in tumor protein p53 play an important role in many human cancers, they are observed in about 50% of all tumors. p53 mutants cause various changes in cellular behavior and function. Accurate computational prediction ...
In recent years pan-resistant microbes have begun to pose a significant risk,particularly in clinical settings. To combat this emerging threat new antimicrobial therapies are required. Antimicrobial peptides (AMPs) are a ...
This dissertation explores the relationship between protein structural and topological properties using computational geometry approach. A representative nonredundant dataset containing 10,220 individual protein chains ...