Molecular Clock Analysis of Human Adenovirus
| dc.creator | Daniel Negrón | |
| dc.date.accessioned | 2022-01-25T19:43:58Z | |
| dc.date.available | 2022-01-25T19:43:58Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Human adenovirus (HAdV) is a diverse pathogen with global circulation that causes sporadic epidemics of acute respiratory disease, keratoconjunctivitis, and gastrointestinal disease. Recombination is a significant driver of adenovirus evolution, generating novel intertypic types. Advances in sequencing technology provides an opportunity to increase the number and availability of genomic samples. Accordingly, this dissertation developed programming libraries to warehouse sequences, standardize metadata, and automate molecular clock analysis. The resulting biosurveillance platform analyzed HAdV genomic sequence data, focusing primarily on species B genotype 55. | |
| dc.identifier.uri | https://hdl.handle.net/1920/12598 | |
| dc.title | Molecular Clock Analysis of Human Adenovirus | |
| thesis.degree.discipline | Bioinformatics and Computational Biology | |
| thesis.degree.grantor | George Mason University | |
| thesis.degree.level | Ph.D. |
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