DNA nanotechnology in neural engineering: A perspective
dc.contributor.author | Vargas, Merlyn | |
dc.date.accessioned | 2020-05-13T19:44:01Z | |
dc.date.available | 2020-05-13T19:44:01Z | |
dc.date.issued | 2020-05 | |
dc.description.abstract | DNA nanotechnology has great potential as a platform to enhance neural engineering approaches. DNA based nanoparticles are biocompatible and easy to functionalize [1]. Peptides or proteins can be conjugated to DNA nanoparticles to target specific cells and tissues [2], [3], as well as imaging agents to help diagnosis and monitoring purposes [4], [5]. In addition, recent studies have shown the capacity of some DNA based nanoparticles to cross the blood-brain barrier to target brain tumors in rats [4]. Others have shown DNA-peptide nanoparticles that enhanced differentiation of neural stem cell proliferation and neural differentiation [6], as well as new technologies to construct DNA-based molecular circuitry [7]. Besides all of these promising features offered by DNA nanotechnology, DNA has also shown to be a great scaffold for the production of nanoelectronics, giving a realistic perspective of the creation of nano devices that can target a desired tissue or cell and perform as nanochips for diagnosis, sensing or modulatory functions. Therefore, this work reviews some of the characteristics of nanotechnology and DNA-based nanoelectronics that are favorable for the development of nanodevices as neural system probes, as well as some perspectives for this type of technology in the field of neural engineering. | |
dc.identifier.orcid | 0000-0002-6234-711X | |
dc.identifier.uri | https://hdl.handle.net/1920/11766 | |
dc.language.iso | en_US | |
dc.rights | Attribution-ShareAlike 3.0 United States | |
dc.rights.uri | https://creativecommons.org/licenses/by-sa/3.0/us/ | |
dc.subject | Neural engineering | |
dc.subject | DNA nanotechnology | |
dc.subject | Neuromodulation | |
dc.subject | Deep brain stimulation | |
dc.title | DNA nanotechnology in neural engineering: A perspective | |
dc.type | Other |
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