Microbiome Analysis in Colorectal Cancer

Simple item page
dc.contributor.advisorGillevet, Patrick M
dc.contributor.authorDadkhah, Ezzat
dc.creatorDadkhah, Ezzat
dc.date.accessioned2018-10-22T01:19:56Z
dc.date.available2018-10-22T01:19:56Z
dc.date.issued2017
dc.description.abstractColorectal cancer (CRC) results from a complex interplay between genes and the environment. Recent studies have focused on the gut microbial population (the microbiota) and its aggregate genome (the microbiome) as one of the environmental players in colorectal tumorigenesis. High-throughput sequencing techniques have added a new dimension to the mining of gut microbiome for biomarkers of CRC and therapeutic targets. Current approaches to microbiome analysis include quantifying the relative abundancies and diversities of microbial populations along with the identification of disease-specific biomarkers.
dc.format.extent244 pages
dc.identifier.urihttps://hdl.handle.net/1920/11285
dc.language.isoen
dc.rightsCopyright 2017 Ezzat Dadkhah
dc.subjectBiology
dc.subjectBioinformatics
dc.subjectClassification
dc.subjectColorectal cancer
dc.subjectMachine learning
dc.subjectMicrobiome
dc.subjectOTU
dc.subjectStatistical tests
dc.titleMicrobiome Analysis in Colorectal Cancer
dc.typeDissertation
thesis.degree.disciplineBiosciences
thesis.degree.grantorGeorge Mason University
thesis.degree.levelPh.D.

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Dadkhah_gmu_0883E_11649.pdf
Size:
7.69 MB
Format:
Adobe Portable Document Format
Download

Collections

College of Science