Molecular Biomarkers and Network Analyses of Neuron-type Connectivity Reveal Cloaked Insights into Hippocampal Function

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dc.contributor.advisorAscoli, Giorgio A.
dc.contributor.authorRees, Christopher Loren
dc.creatorRees, Christopher Loren
dc.date.accessioned2017-01-29T01:16:39Z
dc.date.available2017-01-29T01:16:39Z
dc.date.issued2016
dc.description.abstractTo launch Hippocampome.org, a framework for classifying neuron types in the rodent hippocampus, we assembled >14,000 pieces of experimental evidence supporting knowledge of approximately 3,700 properties for 122 neuron types. This resource, the first comprehensive machine-readable neuron inventory for a mammalian cortical region, provides an opportunity to analyze the hippocampus in novel ways and garner unique insights into its intricate structure and enigmatic function. Here, I describe my two-pronged attack on the sub-cellular and cellular fronts.
dc.format.extent207 pages
dc.identifier.urihttps://hdl.handle.net/1920/10604
dc.language.isoen
dc.rightsCopyright 2016 Christopher Loren Rees
dc.subjectNeurosciences
dc.subjectBioinformatics
dc.subjectConnectomics
dc.subjectGraph theory
dc.subjectHippocampus
dc.subjectMolecular markers
dc.subjectNeuroinformatics
dc.subjectNeuron types
dc.titleMolecular Biomarkers and Network Analyses of Neuron-type Connectivity Reveal Cloaked Insights into Hippocampal Function
dc.typeDissertation
thesis.degree.disciplineBioinformatics and Computational Biology
thesis.degree.grantorGeorge Mason University
thesis.degree.levelPh.D.

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