Narrative Highlights

 

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  • YOUR RESPONSE to posted commentaries
1. Which individual or event do you attribute the greatest historical significance in the advancement of organ replacement devices or machines? Please explain why. 2. What is your most memorable clinical case in which a mechanical device or machine was used as treatment? (answered by clinicians only) 3. What mechanical devices or machines have you had experience with experimentally, and what were the greatest challenges in your work? (answered by scientists and researchers only)

Richard Chan:

The development of the mechanical ventilator ... [more]

Robert Barlett:

Realistically, the most important event was addition of ESRD to Medicare reimbursement ... [more]

John Watson:

Senator Frist's Hasting Lecture (1996) - following the lecture ... [more]

George Pantalos:

Dr DeBakey's meeting with President Johnson to convince him of ... [more]

Benjamin Bangyu Chiang:

Professor Chunshou Ye of Shanghai Second Medical University initiated mechanical assist device research in China ... [more]

Jean Kantrowitz:

The most important thing it that the major developments in artificial organs -- such as dialysis, pacemakers, pump oxygenators -- were ... [more]

Aaron Hill:

C.Walton Lillehei's first cross circulation clinical procedure marked the advent for the routine use of cardiopulmonary bypass ... [more]

Yukihiko Nose:

It is not an individual achievement in this field ... [more]

Leonard Golding:

Saxton (1960) publication re: continuous flow centrifugal blood pumps in animals ... [more]

John Toomasian:

The cross circulation experience of C.Walton Lillehei which led to ... [more]

Arthur Ciarkowski:

Dick Cheney, Vice President of the United States --- Mr Cheney received a dual chamber pacemaker ... [more]

Herman Broers:

Dr Willem Kolff - Why? - for not only starting the field but the circumstances ... [more]

Carl Kjellstrand:

Artificial Kidney -- see Basics - First Steps - Technical Solutions .. [more]

Paul Malchesky:

I would say the Medicare Approval of Chronic Renal Failure treatment. Yes, the technology is important and certainly we cannot ever forget all the contributions made by individuals but without government recognition of the therapy and its support ... [more]


Thomas G. Cody:

I believe that perhaps the seminal set of events (or era) for artificial organs was the immediate postwar period (late forties and early fifties at Peter Bent Brigham Hospital in Boston ... [more]


Monica M. Beyer:

The two things that stand out in my mind as the most revolutionary in
dialysis are not, in fact, machines. The first is the internal arteriovenous fistula developed by Cimino and Breschia... [more]


John Watson:

Most of the actual work [National Heart, Lung, and Blood Institute] was with the intraaortic balloon. The greatest challenge was clinical trials... [more]


Carl Kjellstrand:

In dialysis I think perhaps the "heroic" moment occurred in the early 1940's. A flash point then occurred when simultaneously Alwall in Sweden, Kolff in Netherlands and Murray in Canada independent of each other... [more]


John Watson [response to K.]:

Major novel organ or tissue replacement technologies are usually "disruptive technologies" or as Carl [Kjellstrand] mentioned "flash points"... [more]


Steven J. Phillips:

Heart valve replacement. It demonstrated that a mechanical device would work in a human. [more]

Carl Kjellstrand:

1963 -- Meeting Rolin Eady in Seattle, a fellow doctor, but on dialysis ... [more]

Robert Bartlett:

The first successful ECMO case (described in the 1985 ASAIO Presidential Address) gave us optimis to continue with the project ... [more]

George Pantalos:

In June 1999, there was a young woman who had been supported by an LVAD (left ventricular assist device) for 15 months. Her course had been difficult and compounded by blood clots coming from the device. The decision was made to ... [more]

Steven Phillips:

The first implantation of the intra-aortic balloon pump (IABP) developed by Dr Adrian Kantrowitz -- a 48-year-old woman was dying form cardiogenic shock at Maimonides Hospital in Brooklyn, N.Y. Dr Kantrowitz's team implanted the IABP which ... [more]

Carl Kjellstrand:

It was in 1956 during my first clinical rotation in internal medicine as a young medical student. I was attached to the renal section at University Hospital in Lund. A young woman up north in Sweden had developed acute renal failure late in her pregnancy. She was flown by to the dialysis clinic at Lund - the only one in the country - by the Swedish airforce, which did air-transportation of the very ill in those days. I was the student involved with her and I saw her arrive, comatose, in pulmonary edema and at death's doorsteps with a potassium of about 8 meqv'l and a BUN of over 200 mg/dl... [more]

Steven J. Phillips:

Clarence Dennis [and] Left heart bypass [more]

Leonard Golding:

One of the greatest challenges is convincing people of the potential of continuous blood flow support ... [more]

Don B. Olsen:

I joined Dr. Kolff full time in June 1972. Prior to that date I was a consultant to his artificial heart research. Until 1972 all artificial hearts were implanted into calves/sheep by clinically trained surgeons and they used the mid-sternal approach that was routine to get maximal exposure/access to the heart... [more]


Paul Malchesky:

Perhaps the greatest challenges were at the interface of technology
development and clinical application. When one has a technology/device that meets a clinical need... [more]


Leonard A. R. Golding:

Major challenges have been funding, resources. While NIH funding very important, Must get commercial backing if a device is to go clinical... [more]